Nature

An improved SNAP-ADAR tool enables efficient RNA base editing to interfere with post-translational protein modification

RNA base editing relies on the introduction of adenosine-to-inosine changes into target RNAs in a highly programmable manner in order to repair disease-causing mutations. Here, we propose that RNA ...
Nature

Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases

Innovative approaches to controlled nucleobase-modified RNA synthesis are urgently needed to support RNA biology exploration and to synthesize potential RNA therapeutics. Here we present a strategy ...
mccormick.northwestern.edu

ES_APPM 372: Introduction to the Analysis of RNA Sequencing Data

This course will give an introduction to the theory and practice of analyzing high-throughput RNA sequencing through lectures and hands-on exercises. The basic topics covered will include: 1) the ...
Labroots

From Transcriptomes to Epigenomes: Introduction to single-cell RNA-seq and single-cell ATAC-seq

Single-cell technology has revolutionized the field of biological research by enabling the analysis of individual cells, providing unprecedented insights into cellular heterogeneity and function. More ...