An international study led by a scientist at the University of Ottawa Faculty of Medicine is opening new frontiers in the ...

Anti-PD-1/PD-L1 immune checkpoint blockade (ICB) therapy has revolutionized clinical cancer treatment, while abnormal PD-L1 or HLA-I expression in patients can significantly impact the therapeutic ...

Mitochondria are dynamic organelles that are essential for cellular energy generation, metabolic regulation, and signal transduction. Their structural complexity enables adaptive responses to diverse ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Which neoadjuvant treatment is best for locally advanced esophageal cancer? a systematic review and network meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts ...

New research challenges the traditional explanation for how HDAC inhibitors work against cancer. The results suggest these ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.