Researchers discover that disrupted neuronal microexons cause a permanent spike in cAMP signaling, driving severe hyperarousal, insomnia, and hyperactivity.

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing—a crucial process for isoform expression and protein diversity—is regulated across different ...

Large versus limited molecular profiling panel screening program in patients with metastatic sarcoma: An exploratory subgroup analysis from the ProfiLER 02 trial. This is an ASCO Meeting Abstract from ...

The human heart must constantly adapt to changing demands—a task that requires tightly coordinated molecular shuffling in ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA, ...

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led ...

Alternative splicing (AS) is a genetic process that increases the diversity of proteins that can be generated from genes, by assembling sections of genetic code into different combinations. This is ...